Leptospirosis in elderly patients

Leptospirosis in elderly patients.

Leptospirosis is a re-emerging zoonosis with broad clinical spectrum and high mortality in severe forms. The aim of this study was to analyze clinical manifestations, laboratory findings, epidemiological data, and management in elderly patients with leptospirosis. Toward that end, we performed a descriptive analysis of 15 leptospirosis elderly cases (age 60-78 years) treated at the Clinic of In...

Leptospirosis outcomes in pregnancy

Introduction: Leptospirosis is a serious disease of humans, caused by different strains of the ‎bacteria Leptospira. The disease in humans can include pregnant mothers with poor outcomes ‎such as intrauterine fetal death, abortion, and delivery of a newborn with signs of congenital ‎leptospirosis. Moreover, due to overlapping signs and symptoms, leptospirosis is often ‎difficult...

Leptospirosis in febrile hospital patients in Djakarta.

Cathelicidin Insufficiency in Patients with Fatal Leptospirosis

Leptospirosis causes significant morbidity and mortality worldwide; however, the role of the host immune response in disease progression and high case fatality (>10-50%) is poorly understood. We conducted a multi-parameter investigation of patients with acute leptospirosis to identify mechanisms associated with case fatality. Whole blood transcriptional profiling of 16 hospitalized Brazilian pa...

Pulmonary radiographic findings in 118 leptospirosis patients.

We retrospectively reviewed the medical records and chest radiographs of 118 patients who presented during January 1998 to October 2002 at Songklanagarin Hospital in Hat Yai, Songkhla Province, Thailand who had a high serum immunofluorescent assay titer for leptospirosis. Twenty-nine of 118 (24%) patients had abnormal chest films. Nearly all of these patients had respiratory symptoms and needed...